Astelin (azelastine), a prescription antihistamine nasal spray, has been shown to give quick relief to people with pollen-induced allergy symptoms. The benefits were shown to occur within 15 minutes compared to a placebo (non-medicated) nasal spray, and lasted for many hours. A leading prescription steroid nasal spray, Nasonex (mometasone), was no better than placebo during the 8-hour study.
Astelin is indicated for the treatment of allergic rhinitis as well as non-allergic rhinitis. Generally speaking, prescription nasal sprays have not been previously shown to work within a short period of time, and typically need to be used for days before they start to work. This study suggests that Astelin may be used on an as-needed basis, and unlike over the counter nasal decongestants (such as Afrin), can be used for long periods of time.
Was the Nasonex just started and used for the 8 hour study, or had the Nasonex been used for a period of time? I guess everyone should realize that Nasonex is designed for relief after 10 days of use, not immideately.
Elaine,
Both medications were administered one time and symptoms were then followed for 8 hours during exposure to ragweed pollen.
This study drives home the point that nasal steroids do not work well on an “as needed” basis, although Astelin does! Most of my patients begin to get better with nasal steroids within a few days, probably before 10 days of use.
Thanks!
Astelin is a great find in the world of allergies. Even when I feel a headache coming on,usually allergies or barometer,it works wonders.
How come it’s taken so long for it to be prescribed?
I had to go to my doctor Jan 6, 2010 for help with “rebound” effect of long term (several months) use for OTC nasal sprays. I had to use the OTC sprays every day before to keep my sinuses open. My doctor prescribed Astelin. I usually sprayed my nose at bedtime, but I began using this new medication vs. the OTC stuff. The effects were immediate, my sinuses remained cleared throughout the night and day, and though it has only beena few days since I began treatment I have not picked up the OTC spray bottle again.