Why is SLIT Not Yet FDA Approved?
Multiple studies are currently being conducted for the purpose of trying to get SLIT approved in the United States, but is it likely that approval is at least a few years away. Until the FDA approves the use of SLIT, most mainstream allergists will not offer this type of therapy, and insurance companies will not cover the costs of the therapy. Some health-care professionals are offering SLIT, but people should use extreme caution and talk with a reputable allergist before choosing this non-FDA approved treatment.Questions that remain to be answered prior to SLIT receiving FDA approval:
- What is the effective dose, dosing regimen and timing of SLIT?
- How can multiple allergens be given in an effective, convenient and cost-effective way?
- Is SLIT safe for high-risk groups?
- What is the significance of the known side effects?
How Does SLIT Compare with Traditional Allergy Shots?
Traditional allergy shots are a proven therapy in treating allergic rhinitis, allergic conjunctivitis, allergic asthma and venom allergy for nearly a century. Allergy shots have been FDA proved for many years, although they need to be given in a physician’s office due to the potential for severe side effects. Therefore, they may be an inconvenience to many people.Studies comparing the efficacy of traditional allergy shots and SLIT show that allergy shots are better at treating allergic rhinitis and asthma symptoms. In addition, immunologic markers and other tests that correlate with response to immunotherapy are seen less commonly in people receiving SLIT. Therefore, while allergy shots appear to be superior at treating allergic disease, SLIT will likely become an important treatment option for people unwilling or unable to receive allergy shots.
Want to keep learning? Read more about traditional allergy shots.
Sources:
Cox LS, Linnemann DL, Nolte H, Weldon D, Finegold I, Nelson HS. Sublingual Immunotherapy: A Comprehensive Review. J Allergy Clin Immunol. 2006;117:1021-35.
Potter PC. Update on Sublingual Immunotherapy. Ann Allergy Asthma Immunol. 2006;96:S22-5.
DISCLAIMER: The information contained in this site is for educational purposes only, and should not be used as a substitute for personal care by a licensed physician. Please see your physician for diagnosis and treatment of any concerning symptoms or medical condition.
