How to Know if You Have a Spice Allergy

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Spices are unlikely sources of an allergy. With that being said, spice allergies have been known to occur. Some common spice allergies include capsaicin (found in hot peppers), cinnamon, garlic, black pepper, and vanilla.

Spice allergies are thought to affect only about 2% of adults. Symptoms of a spice allergy can range from mild to life-threatening.

This article discusses spice allergies and their symptoms. It also explains how healthcare providers diagnose them, and what you can do to both treat and prevent reactions.

spice allergy symptoms

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Spice Allergy Symptoms

Some normal physiological responses can occur in anyone who eats certain spices. For example, chili or wasabi may cause immediate watering of the eyes and burning in the mouth in anyone who consumes them.

The reaction is not due to an allergic response, but to the chemical compounds they contain (capsaicin and allyl isothiocyanate, respectively). These irritate the mucous membranes of the nose and mouth.

This may be mistaken for an allergic reaction to a spice. However, with a spice allergy, there may also be other symptoms such as:

Others still may experience shortness of breath or develop a rash where the spice comes in contact with skin. This is known as contact dermatitis.

Spices are rarely eaten by themselves, and dishes that contain them often include a blend of different seasonings—not just one. Because of this, it can be hard to tell if a certain spice or the food it is in is to blame for a reaction.

Heating certain spices may neutralize the allergens, but some allergens aren't affected by heat. For example, Api g 1, the primary allergen found in celery and celery spice, is not vulnerable to heat. The allergen in mustard seeds has also been shown to be heat-resistant.

Symptoms of Anaphylaxis

In some cases, a potentially deadly, full-body allergic reaction known as anaphylaxis can occur.

Symptoms of anaphylaxis are typically severe and may include:

Anaphylaxis is considered a medical emergency that requires immediate 911 assistance. Even if symptoms appear to get better on their own, they can return hours later—even if you haven't been exposed to the spice a second time.

If left untreated, anaphylaxis can rapidly progress and lead to:

  • Coma
  • Shock
  • Cardiac or respiratory failure
  • Death

Diagnosing a Spice Allergy

If your healthcare provider thinks you have a spice allergy, they may perform an allergy test.

Most allergy tests involve applying skin patches, but not all spices can be tested this way. This is especially true for hot spices that can inflame and irritate the skin.

There are some blood-based allergy tests available. But here, too, many of them can't test for the broad range of potential spice allergens.

This all means that your personal experience is extremely important to making an allergy diagnosis. Repeated episodes can usually help narrow down what you may be allergic to.

Intolerance vs. Allergy

A spice intolerance is usually limited and can resolve without treatment, while an allergy can be life-threatening. However, both allergies and intolerances can have some of the same symptoms. For example, an intolerance can cause a rash or itchy mouth, which are some of the same symptoms as an allergy. That's why it's important to see an allergist for a diagnosis.

Pay attention to the foods you eat, what they contain, and how you feel after eating them. Report all of this information to your healthcare provider (the more detail, the better).

Food Allergies Doctor Discussion Guide

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Treating a Spice Allergy

The treatment of a spice allergy depends on the type and severity of symptoms experienced. Among the options:

  • For an uncomplicated allergy (not involving medical complications), oral antihistamines can provide relief by blocking the activity of histamine. This is a chemical released by the immune system that triggers allergy symptoms.
  • For contact dermatitis, a topical corticosteroid cream can help reduce inflammation and redness.
  • Oral corticosteroids may be prescribed in more extreme cases. Corticosteroid nasal spray can help relieve nasal congestion.
  • If you're at risk of anaphylaxis, an epinephrine injection can provide immediate relief. It does this by relaxing the smooth airway muscles and blood vessels.

An EpiPen injection provides immediate relief when you are experiencing a life-threatening allergic reaction. But if you have symptoms of anaphylaxis, you should still go to the emergency room and seek immediate medical care.

Preventing a Spice Allergy

Ultimately, the best way to deal with a spice allergy is to avoid the spice in question. Unfortunately, this is easier said than done.

Many foods are pre-seasoned or use seasoning agents made from multiple herbs, spices, and chemicals. Dishes prepared in a restaurant may include spices not called out on a menu.

A person is rarely allergic to just one type of spice. There is a high cross-reactivity between spices, nuts, and even tree pollens. This means that the chemical structure of certain foods is so similar that they both can trigger an allergic response.

Examples of cross-reactivity include:

  • Oregano and thyme
  • Onion and garlic
  • Paprika and mace
  • Mustard and rapeseed
  • Mustard and tree nuts
  • Sesame and tree nuts
  • Cottonseed and walnut
  • Birch pollen and various spices
  • Mugwort pollen and various spices
  • Celery and various spices
  • Carrot and various spices
  • Fenugreek and peanut

Given this, a person with a severe allergy may need to avoid all spices until they find the allergen or allergens that are causing the problem.

They may also need to carry an EpiPen or a pre-loaded epinephrine syringe to use in case they experience a severe reaction.

Summary

Although it's rare for someone to have a spice allergy, it can sometimes occur. People may even experience severe allergic reactions when they eat particular spices.

Most allergy tests only test for a small variety of spices. This is why you should pay close attention to the foods you eat. If you repeatedly experience allergic reactions to certain foods, this can help you pinpoint which spice allergens cause you to feel sick.

6 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Bradatan E, Sabouraud D. Spice reactions in children: allergic or not? Cases reports and literature review. World Allergy Organ J. 2020;13(8).

  2. SŁowianek M, Majak I, LeszczyŃska J, et al. New allergens from spices in the Apiaceae family: anise Pimpinella anisum L. and caraway Carum carvi L. Cent Eur J Immunol. 2020;45(3):241-247. doi:10.5114/ceji.2020.101236

  3. Rib-Schmidt C, Riedl P, Meisinger V, et al. pH and heat resistance of the major celery allergen Api g 1. Mol Nutr Food Res. 2018;62(15):e1700886. doi:10.1002/mnfr.201700886

  4. Frigerio J, Pellesi R, Mezzasalma V, et al. Development of a DNA barcoding-like approach to detect mustard allergens in wheat flours. Genes (Basel). 2019;10(3):234. doi:10.3390/genes10030234

  5. ACAAI Public Website. Anaphylaxis: Causes, symptoms & treatment.

  6. American Academy of Allergy, Asthma, & Immunology. Can spices cause allergic reactions?

Daniel More, MD

By Daniel More, MD
Daniel More, MD, is a board-certified allergist and clinical immunologist. He is an assistant clinical professor at the University of California, San Francisco School of Medicine and formerly practiced at Central Coast Allergy and Asthma in Salinas, California.