Definition: Chemical released from mast cells and basophils upon binding of allergen to IgE on the surface of these cells, resulting allergic activation. Results in allergic symptoms such as hives and itching of the skin, and increase of allergic rhinitis symptoms.
Histamine
By Daniel More, MD, About.com Guide
Updated December 11, 2006
About.com Health's Disease and Condition content is reviewed by our Medical Review Board
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