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# Latex Allergy

## Could You Be Allergic to Latex?

Updated September 14, 2011

Contact dermatitis to latex may produce an itchy rash, redness, blisters and scaling, or may cause the more severe anaphylaxis.

Updated September 14, 2011

### What are the symptoms of latex allergy?

Latex is the major ingredient in most rubber products, and is made from the tree Hevea brasiliensis. Thousands of household and occupational products contain latex, from shoes to rubber bands. This material is especially common in the health care industry, where it can be found in surgical gloves, and various pieces of medical equipment.

There is much confusion surrounding the topic of latex. Latex is not the same as many synthetic rubber materials, such as butyl or petroleum-based synthetic products. Paints that are labeled, “latex-based”, contain a synthetic product that has not been shown to cause problems for people with latex allergy.

### Who gets latex allergy?

The tendency to develop allergies is inherited. As with other allergies, the more intense and frequent the exposure to latex, the more likely you will develop an allergy to it. Up to 5 to 10% of healthcare workers develop latex allergy as a result of repeated exposure to latex containing products. The decreased use of powdered latex gloves (most latex gloves are now non-powdered) seems to have decreased the occurrence of latex allergy in healthcare professionals.

Other groups at risk for latex allergy include those who have had various surgeries, especially those involving the nervous system and genitourinary tract system. Children with spina bfida appear to have a high occurrence of latex allergy.

### What are the symptoms of latex allergy?

In general, there are two ways a person can experience allergic reactions to latex, immediate reactions and delayed reactions.

Delayed latex allergy. Delayed reactions to latex consist of itchy, red and mildly swollen rashes that appear only at the sites of contact with the latex product. These rashes typically appear within 12 to 24 hours after exposure, and are not life threatening. These reactions are similar to those caused by poison oak (contact dermatitis), and are due to other chemicals used in the making of latex, rather than the latex protein itself.

Immediate latex allergy. These potentially serious reactions occur within minutes of exposure and may cause hives, itching at the site of contact or all over, tightness of the throat, wheezing, difficulty in breathing, anaphylaxis and even death. Most people may experience these reactions only upon contact with the latex product. Others are so sensitive that they may have a reaction after being given a drug stored in a bottle with a latex stopper or after breathing the powder that comes off latex surgical gloves.

### How is latex allergy diagnosed?

Delayed latex allergy. People with this type of reaction to latex often do not have allergic antibody (IgE) against latex, but can be diagnosed with the use of a patch test. This involves placing other components of the latex (not the latex protein itself) on the skin for approximately 48 hours, and interpreting the results of the test at 48 to 96 hours. This test should only be performed by a physician experienced in the diagnosis of allergies.

Immediate latex allergy. This type of latex allergy is due to the presence of IgE against latex, and diagnosed with the use of skin testing or RAST. Skin testing to latex may be difficult, since there is no commercial latex extract available for skin testing in the United States. Some allergists make their own extract, and many others rely on the RAST for making a diagnosis of latex allergy. These tests should only be performed by a physician experienced in the diagnosis of allergies.

### Are there foods that are related to latex allergy?

Many people with immediate latex allergy will also have the oral allergy syndrome. This is a condition in which a latex-allergic person notices itching and swelling of the mouth after eating certain foods, most commonly banana, melons, avocado, kiwi, and chestnuts. This is due to the presence of proteins in the foods that are similar to those found in the latex. Not all people with latex allergy to react to any or all of these foods.

While most of the oral allergy symptoms are mild and last only a few minutes, some people can experience more severe reactions to these foods. It is best for a person with latex allergy to avoid any food that causes the oral allergy syndrome (or any other concerning symptoms).

### How is latex allergy treated?

Avoidance of latex. The best way to prevent allergic reactions is to avoid exposure to latex. However, latex is extremely common, so avoidance may be difficult. Inform your doctor and dentist that you are latex allergic, so they will use non-latex gloves and other latex-free medical supplies during any care that is provided.

Household latex is found in latex balloons, dishwashing gloves and in latex condoms. These items are known to commonly cause reactions in latex-allergic people. Items less likely (but still possible) to cause a reaction include rubber bands, erasers, rubber toys, elastic in clothing and baby nipples and pacifiers. Read the labels on any rubber product before purchase, and avoid using any of these that contain latex.

Any person with latex allergy undergoing surgery needs to carefully coordinate the procedure with the hospital, surgeons, anesthesiologists, and other medical personnel to ensure that no latex is used during the procedure. This often means that a latex-allergic person is the first surgery of the day, to ensure the operating room is thoroughly cleaned the night before, and that there is no latex contamination from surgeries earlier in the day.

Allergy shots, or immunotherapy, to latex has been tried to prevent reactions with latex exposure, although with mixed results. Another therapy, omalizumab (Xolair®), an injectable anti-allergic antibody used for the treatment of severe asthma, has been tried to prevent reaction in people suffering from severe latex allergy. It is important to note that both of the above therapies are only experimental at the present time.

Daniel More, MD

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