Two studies, one published in 2008 and the other in 2010, showed that the use of Flonase (fluticasone propionate) along with Astelin (azelastine) resulted in additional allergy symptom control than either medication alone. The additional benefit was not small – the combination of Flonase and Astelin resulted in approximately 40% improvement in allergy symptoms compared to either medication alone. This improvement not only applied to nasal symptoms, but to eye symptoms as well. Interestingly, the 2010 study involved the use of a single nasal delivery device to administer both medications –- suggesting that a single product containing both medications may soon be available in the near future.
Learn more about the use of nasal sprays for the treatment of allergies.
Hampel FC, Ratner PH, Van Bavel J, et al. Double-Blind, Placebo-Controlled Study of Azelastine and Fluticasone in a Single Nasal Spray Delivery Device. Ann Allergy Asthma Immunol. 2010; 105:168-173.
Ratner PH, Hampel F, Van Bavel J et al. Combination Therapy with Azelastine Hydrochloride Nasal Spray and Fluticasone Propionate Nasal Spray in the Treatment of Patients with Seasonal Allergic Rhinitis. Ann Allergy Asthma Immunol. 2008; 100:74-81.
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