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Readers Respond: Dealing With Sulfa Drug Allergy
Responses: 73

By Daniel More, MD, About.com

Updated May 12, 2009

User responses are not monitored by About.com's Medical Review Board.

From the article: Sulfa Drug Allergy
There are numerous medications that contain sulfa molecules. Some very sensitive people have allergic reactions to many of these drugs, and so they go to great lengths to make sure that they don't take these medications accidentally. Are you one of them? Share how you've been able to deal with being allergic to sulfa drugs and avoid such reactions. Share Your Experiences

Other meds for UTI

I also can not take sulfa meds or penicillins, in fact, there is not a lot of antibiotics I can take. So, the dr. just looks at the allergies, and asks me which ones I can take. Usually it is Biaxin for URI, and I can take Cipro for UTI's.I usually have to take these meds for 10 days. These are the only ONES that do no give me shortness of breath,itching, or anaphylaxis at present. Hope this helps!
—Guest Jody

Serious bactrim reaction

When I was 7 years old my Dr. prescribed me bactrim for treating UTI. After 5 days I started having a rash all over my body, it was itchy and very red. Finally, I had a panic attack and high fever, which led to stevens johnsons syndrome. After 4 days of my episode, my lips, as well as my inner part of the mouth and nose, started to show blisters and burns, and I felt terrible. So, doctors determined that I was allergic to Sulfa. Now, after 9 years, I had an injury in my knee (meniscus) and I was prescribed Celebrex... I dindt feel nothing strange, and now, reading your experiences, I find out it contains sulfa.. thanks god I didnt show any reaction!!!
—Guest Raffa

Sulpha allergy

I finished a round of Septra-sulfa penicillin for a UTI. I was on it for 5 days. I felt sick the whole time - headache, fatigue and even vomitted once. A day after I was done the meds I started getting large itchy rashes all over my body - legs, arms, back. It has been 3 days since then and my hands, feet and lips are swelling. I saw my Dr yesterday and she said just to take Benalyn to treat the symptoms. She noted that I am allergic to sulfa meds and told me that I could continue to have reaction symptoms for the next 2 weeks. I am also experiencing itchy throat and am not sure if I should go the the Dr again or emergency or just wait.
—Guest Maura

Sulfa Allergy-No Problem

I am allergic to sulfa drugs and have been aware of this since childhood. I have never experienced an issue with a practitioner being unale to treat me with non-sulfa drugs. I make the clinic aware of my allergy before treatment is even up for discussion. I have, however, had my allergy reconfirmed. Last year I had a horrible upper-respiritory infection and no insurance so I used some of my mother's cough syrup. I noticed before I took it that it seemed to have milky/chalky properties of the straight syrup that I've always been prescribed in the past. Despite this, I still took the medicine and within 30min I was vomiting like crazy! When I googled the medication I found out too late that it was a sulfa drug. Lesson learned!
—Guest Crystal

Silvadene caused skin allergy

I was given Silvadene to apply to a large burn on my legs. I used it daily, applying it with my bare hands, for a month. I was unaware that it contained a sulfa component. by the end of the month, I developed a skin reaction that was thought to be dyshydrotic Exzema, but later on, was seen as a chronic reaction to sulfonimides. Now, I have an auto-immune response-type allergy that regularly flairs up, covering my hands with deep vesicles, which is followed by massive skin peeling. I'm now at my wit's end with the news that I will have this problem the rest of my life.
—Guest Peter

report of allergy to sulfa

The About.com article on sulfa reactions to celebrex said no reports of allergic reactions had been reported. I have a history of sensitivity to sulfa. I used it once and broke out in bright red, itchy skin reactions on my back and chest. It continued for a day or two. So much for using celebrex.
—sulfa_ruth

one dose was enough for me

I haven't taken an antibiotic for 35 years, but have always managed illness with herbal remedies. I developed my first ever UTI over the weekend and decided to go to a clinic to get checked. The doctor gave me a prescription for Bactrim. I was drinking unsweetened cranberry juice and taking cranberry pills but had been told this might not take care of the bacteria. I took one pill before bedtime. Early in the morning, I noticed about a dozen hives on my lower extremities. I did not take any more pills. A few hours later, I had loose stool and vomited. When I called the clinic, I was told to come in and get ANOTHER prescription. I went out right out and got a herbal compound that targets UTIs. Frankly, I am astonished at the level of ignorance out there about natural healing. In fact, when I told the doctor how I had taken care of myself fior 35 years, he laughed at me. That's the last time I go into a clinic.
—Guest millie

Bad Sulfa Allergy

I had a skin infection on my knee i went to the ER they gave me bactrim i took it for 8 days and was supposed to take it ten on the 7th day i had a few red bumps that looked like fla bites, the next morning i was covered it a red rash itching like crazy. i went back to the ER i had the chills i had a bad cough and a 101.9 fever it was hot out and i was freezing i stopped taking the bactrim and now i feel horrible im still covered and im itchy like crazy. I took an oatmeal bath and it didn't help. this is the worst thing ive ever had never take sulfa
—Guest Paige

what to take

I guess what I was trying to ask in my last note is there anyone who has found a drug they can take for UTI's that isn't one of the sulfa, amoxicillen, etc. drugs....
—Guest Annie

Septra Anaphyaxis reaction after 10 yrs

I had taken septra for 10 yrs for monthy UTI's. The last time I took it I was at work and within minutes a coworker asked me what was wrong. I felt nothing but was covered in red splotches that look like a bad sunburn. It started on my head and covered my body. Seconds later I was having trouble breathing and itching all over. I had an inhaler and I think it saved my life. by helping my airway long enough to get to the ER which was 10 min away. In the ER the only thing I recall is being put on oxygen and an IV. I also recall the benadryl did not work and they gave me more until they could not give any more. This was 17yrs ago so I'm sure care has changed. I have had an Epi-pen for 7 yrs. My second anaphyaxis reaction happened last yr in the hospital during allergy testing and I was given epinephrine right away but still had to stay in the hospital. So just because you never had a reaction does not mean you won't one day. Just be careful.
—Guest Alyx

no sulfa, what to take for UTI

I am very confused...Have a bladder infection, they gave me Trimpex which is a sulfa drug, but I have been afraid to take it..The Dr. looked at me and said I dont' know what to do for you if you can't take the bactrim, septra or any sulfa drug...do we have to suffer with UTI's because no one can help us?
—Guest annie

Sulfa Drugs and foods

I was given a sulfa drug for a UTI in high school. I was out of school for a week and could not eat, went to the doctor 4 times, and finally was put on a different medicine. No one said I had an allergy, and it was prescribed again last year for the same thing. This time it got so bad, I could not get out of bed other than to vomit, which I did regularly. After a week, I called my doctor about having a fever of 105 for over a day even after taking Tylenol. The nurse said to wait another day, drink fluids, and take more Tylenol, which I did and then threw back up. Finally I was taken to the hospital, informed I was allergic to sulfa, pumped full of fluids and sent home after three hours. Later I had a similar reaction to a multivitamin and saw that it had two sulfate compounds. I now take a sulfur-free one just fine. Diet soda and Egg Beaters also contain sulfate. Diet drinks and sulfur vitamins make me vomit and Egg Beaters put me in shock. Anyone else have this problem?
—Guest Tracy

Be Educated...Beware!

After mentioning to my Dr. that my sister was allergic to sulfa drugs and two other antibiotics didn't work; he prescribed it anyway. I was being treated for a non-mrsa staph. Long story short...after the 4th day I began feeling "very nervous, cold,fast heart rate. I just thought it was my nerves, after the 9th day I broke out in hives all over my body,hot/red face and began having severe panic attacks between that time. I contacted my doctor who was out and a "sub" suggested taking a steroid...NOT! I would ride it out..it is day 7 after stopping the drug and I STILL feel nervous and not myself. The pharmasist told me when I got the drug to drink plenty of water to "flush it out" I only wonder how I would have been had I not been told to do that. My infection looks like it is under control, but not completely. It was a nightmare and I highly recommend to be cautious in taking any sulfa drug. Bactrim has been pulled due to the expense and sulfa is cheaper via insurance cos.
—Guest Lori Ann

Sulfa Drug/Septra

My son was in the hospital for the swine flu and pneumonia, and I had pain urinating. My doctor called me in Septra to the hospital pharmacy. Several days later, we left the hospital and went back home and had no reactions to anything. On the last day of my last dose, I woke up to a rash on my upper thighs and upper arms and back. I felt horrible and had a mild fever up to 101. I took 2 benadryl which knocked me for a loop and I slept most of the day and night, with hardly no energy or appetite. The next day, I am itching like crazy with almost NO relief. Cold showers help for a few minutes. Keeping clothes away from the rash helped some, and Aveeno baby body wash decreased the itching. My rash spread and became full red blotches where they began as merely red dots (similar to chicken pox). I have never felt so much itching in my life. I would highly recommend NEVER taking this type of medicine or other sulfa drugs. Had I read this site earlier, I would have asked for different meds.
—Guest Kim

Bactrim sucks!

I am a poor college student without any health insurance. For months my nose was bugging me, it felt really dry and I had these weird painful boogers all the time. Finally I went to a doctor who diagnosed a severe, persistent sinus infection that I had probably had for 5 months and he gave me bactrim for it. After 5 days I called the office and left a message for the doctor saying I was experiencing intense pain in my kidneys, had a. Rash and was throwing up about 4 hours after I took my pill. A med assisstant said she would call me back after talking to the doctor. When she called back she told me that with an infection like mine pain is to be expected and that I need to keep taking the bactrim 3 times a day. I was out of work and about 2-3 weeks in just felt awful. I hadn't been able to eat for 14 days but my whole body swelled up. Rash spread to my face and the pain in my lower back was excruciating. My job asked me to show up for a meeting and I drove myself there. I don't remember
—Guest Evie

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